Thermal injury disrupts normal hemostasis and sets off a cascade of everts: cellular alterations and release of inflammatory mediators cause hypovolemic and cellular shock. Fluid resuscitation in burn injuries has been in use for more than a century, and much research has been devoted to development of resuscitation formulas and appropriate choice of fluid. Parameters for adequate monitoring of resuscitation are greatly debated. Current research efforts focus on minimizing burn edema through mediator modulation and on development of definitive endpoints of resuscitation monitoring.
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Controvesier in Trauma Resuscitation| February 01 1999
Initial Resuscitation After Burn Injury: Therapies, Strategies, and Controversies
Karla S. Ahrns, RN, BSN, CCRN;
AACN Adv Crit Care (1999) 10 (1): 46–60.
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Karla S. Ahrns, Deborah K. Harkins; Initial Resuscitation After Burn Injury: Therapies, Strategies, and Controversies. AACN Adv Crit Care 1 February 1999; 10 (1): 46–60. doi:
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