Causes of sudden infant death syndrome (SIDS) remain elusive. Much of the current literature points to an infectious cause with a role for proinflammatory cytokines and septic shock in stimulating an overwhelming response in an infant. This article reviews the literature and possible causes of this devastating condition.
Pathophysiology| May 01 2000
Sudden Infant Death Syndrome: A Toxic Response
Jane Blood-Siegfried, DNSc, CPNP
From Duke University School of Nursing, Durham, North Carolina.
Reprint requests to Jane Blood-Siegfried DNSc, CPNP, Duke University, School of Nursing, PO Box 3322, Durham, NC 27710; e-mail: firstname.lastname@example.org
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AACN Adv Crit Care (2000) 11 (2): 300–308.
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Jane Blood-Siegfried; Sudden Infant Death Syndrome: A Toxic Response. AACN Adv Crit Care 1 May 2000; 11 (2): 300–308. doi:
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