Weight loss in patients with chronic obstructive pulmonary disease has a negative effect on the clinical course of the patient. Causes of weight loss in this population are known to include the effects of an energy imbalance, increased cytokines, hypoxia, and glucocorticoid use. This article delineates mechanisms included in these processes and highlights specific deleterious aspects of each. In addition, the effects of the following therapies are discussed in light of recent research findings: nutrition support, anabolic steroids, recombinant human growth hormone, and polyunsaturated fatty acids. This review summarizes the current state of knowledge in this area.
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Respiratory Nursing| May 01 2001
Malnutrition in Chronic Obstructive Pulmonary Disease: Adding Insult to Injury
Jean K. Berry, PhD, RN, CS;
*From College of Nursing, University of Illinois at Chicago, Chicago, Illinois.
†From College of Medicine, University of Illinois at Chicago, Chicago, Illinois.
Reprint requests to Jean K. Berry, PhD, RN, CS, Clinical Assistant Professor, Medical Surgical Nursing, 845 S. Damen Avenue, University of Illinois at Chicago, College of Nursing M/C802, Chicago, IL 60612; e-mail: firstname.lastname@example.org
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AACN Adv Crit Care (2001) 12 (2): 210–219.
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Jean K. Berry, Charles L. Baum; Malnutrition in Chronic Obstructive Pulmonary Disease: Adding Insult to Injury. AACN Adv Crit Care 1 May 2001; 12 (2): 210–219. doi:
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