Until recently, sudden cardiac death in a young person often remained an unexplained tragedy. However, in the last decade there have been dramatic advances in medical knowledge regarding inheritable dysrhythmias that increase the risk of SCD in otherwise healthy young individuals. The primary mechanism in this group of dysrhythmias appears to be an alteration of cardiac repolarization. In some diseases, the specific genes affected and even precise cellular mechanisms have been identified. The information about these diseases is often complex and rapidly evolving, challenging both healthcare providers and the families who must make important decisions based on emerging and incomplete information. The purpose of this article is to describe current understanding of the repolarization-related dysrhythmias and discuss the clinical implications for advanced practice nurses.
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Electrophysiology and Device Therapy| July 01 2004
Long QT Syndrome and Other Repolarization-related Dysrhythmias
Sarah S. LeRoy, RN, MSN;
From the University of Michigan Congenital Heart Center (Ms LeRoy), and the Department of Pediatrics and Communicable Diseases, University of Michigan (Dr Russell), Ann Arbor, Mich.
Reprint requests to Ms LeRoy, Pediatric Nurse Practitioner, University of Michigan Congenital Heart Center, 1500 Medical Center Dr, Ann Arbor, MI 48109-0204 (firstname.lastname@example.org).
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AACN Adv Crit Care (2004) 15 (3): 419–431.
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Sarah S. LeRoy, Mark Russell; Long QT Syndrome and Other Repolarization-related Dysrhythmias. AACN Adv Crit Care 1 July 2004; 15 (3): 419–431. doi:
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