Critical illness polyneuromyopathy, a complication of critical illness, is a primary axonal degeneration of motor and sensory fibers that leads to skeletal muscle weakness. It significantly contributes to the unexplained difficulty in weaning from mechanical ventilation and to their prolonged rehabilitation and poor quality of life after discharge. This article will discuss the diagnosis of critical illness polyneuromyopathy, identify risk factors, review several pathomechanisms that have been proposed, and discuss the implications for practice.
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Symposium: Prevention of Complications in Critical Illness| April 01 2007
Neuromuscular Complications in the Intensive Care Unit: Critical Illness Polyneuromyopathy
AACN Adv Crit Care (2007) 18 (2): 167–182.
Karen L. Johnson; Neuromuscular Complications in the Intensive Care Unit: Critical Illness Polyneuromyopathy. AACN Adv Crit Care 1 April 2007; 18 (2): 167–182. doi: https://doi.org/10.4037/15597768-2007-2009
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