The effectiveness of transfusions is often compromised by adverse reactions. Common transfusion reactions (hemolytic transfusion reactions, transfusion-related acute lung injury, transfusion-associated circulatory overload, transfusion-related immunomodulation) are reviewed, including pathogenesis, clinical and laboratory manifestations, and treatment. In addition, artificial blood substitutes are discussed as a way to mitigate the risk of transfusion-related morbidity and mortality.
Symposium: Hematology Issues in Critical Care| April 01 2009
Blood Transfusion: Friend or Foe
Elizabeth A. Katz, RN, MS, CCRN, ACNP
AACN Adv Crit Care (2009) 20 (2): 155–163.
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Elizabeth A. Katz; Blood Transfusion: Friend or Foe. AACN Adv Crit Care 1 April 2009; 20 (2): 155–163. doi: https://doi.org/10.4037/15597768-2009-2007
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