Mortality rates of critically ill patients have decreased markedly in recent years thanks to advancements in care.1 Given the improved survival rates of critically ill patients, investigators have broadened their focus from short-term mortality to long-term mortality and morbidities that are often underrecognized by intensive care unit (ICU) practitioners. The Society of Critical Care Medicine (SCCM) has defined post–intensive care syndrome (PICS) as a new or worsening decrement in mental, cognitive, or physical health following critical illness that persists beyond the acute hospitalization.2 Many medication-related risk factors are associated with development of cognitive impairment in critically ill patients, including glucose dysregulation,3,4 delirium,5 and medications.6 Medications have also been associated with acute neuromuscular weakness following an ICU admission.7 In the past decade, the increased risk of adverse drug events (ADEs) during transitions of care has become widely known. This column focuses on how...
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1 April 2016
Drug Update|
April 01 2016
Medication Management to Ameliorate Post–Intensive Care Syndrome
Joanna L. Stollings, PharmD, BCPS;
Joanna L. Stollings, PharmD, BCPS
Joanna L. Stollings is Clinical Pharmacy Specialist in the Medical Intensive Care Unit (MICU) and Pharmacist in the ICU Recovery Center, Department of Pharmaceutical Services, Vanderbilt University Medical Center, 1211 Medical Center Drive, BUH-131, Nashville, TN 37232 ([email protected]). Sarah L. Bloom is Acute Care Nurse Practitioner in the MICU and the ICU Recovery Center, Department of Medicine, Vanderbilt University Medical Center. Elizabeth L. Huggins is Acute Care Nurse Practitioner, Department of Medicine, Vanderbilt University Medical Center. Scottie L. Grayson was a patient in the ICU Recovery Center at Vanderbilt University Medical Center. James C. Jackson is Neuropsychologist and Assistant Director of the ICU Recovery Center, Center for Health Services Research, Department of Medicine, Department of Psychiatry, Vanderbilt University Medical Center, and Geriatric Research, Education and Clinical Center (GRECC) Service, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, Tennessee. Carla M. Sevin is Assistant Professor of Medicine and Director of the ICU Recovery Center, Vanderbilt University Medical Center.
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Sarah L. Bloom, AG-ACNP;
Sarah L. Bloom, AG-ACNP
Joanna L. Stollings is Clinical Pharmacy Specialist in the Medical Intensive Care Unit (MICU) and Pharmacist in the ICU Recovery Center, Department of Pharmaceutical Services, Vanderbilt University Medical Center, 1211 Medical Center Drive, BUH-131, Nashville, TN 37232 ([email protected]). Sarah L. Bloom is Acute Care Nurse Practitioner in the MICU and the ICU Recovery Center, Department of Medicine, Vanderbilt University Medical Center. Elizabeth L. Huggins is Acute Care Nurse Practitioner, Department of Medicine, Vanderbilt University Medical Center. Scottie L. Grayson was a patient in the ICU Recovery Center at Vanderbilt University Medical Center. James C. Jackson is Neuropsychologist and Assistant Director of the ICU Recovery Center, Center for Health Services Research, Department of Medicine, Department of Psychiatry, Vanderbilt University Medical Center, and Geriatric Research, Education and Clinical Center (GRECC) Service, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, Tennessee. Carla M. Sevin is Assistant Professor of Medicine and Director of the ICU Recovery Center, Vanderbilt University Medical Center.
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Elizabeth L. Huggins, AG-ACNP;
Elizabeth L. Huggins, AG-ACNP
Joanna L. Stollings is Clinical Pharmacy Specialist in the Medical Intensive Care Unit (MICU) and Pharmacist in the ICU Recovery Center, Department of Pharmaceutical Services, Vanderbilt University Medical Center, 1211 Medical Center Drive, BUH-131, Nashville, TN 37232 ([email protected]). Sarah L. Bloom is Acute Care Nurse Practitioner in the MICU and the ICU Recovery Center, Department of Medicine, Vanderbilt University Medical Center. Elizabeth L. Huggins is Acute Care Nurse Practitioner, Department of Medicine, Vanderbilt University Medical Center. Scottie L. Grayson was a patient in the ICU Recovery Center at Vanderbilt University Medical Center. James C. Jackson is Neuropsychologist and Assistant Director of the ICU Recovery Center, Center for Health Services Research, Department of Medicine, Department of Psychiatry, Vanderbilt University Medical Center, and Geriatric Research, Education and Clinical Center (GRECC) Service, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, Tennessee. Carla M. Sevin is Assistant Professor of Medicine and Director of the ICU Recovery Center, Vanderbilt University Medical Center.
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Scottie L. Grayson;
Scottie L. Grayson
Joanna L. Stollings is Clinical Pharmacy Specialist in the Medical Intensive Care Unit (MICU) and Pharmacist in the ICU Recovery Center, Department of Pharmaceutical Services, Vanderbilt University Medical Center, 1211 Medical Center Drive, BUH-131, Nashville, TN 37232 ([email protected]). Sarah L. Bloom is Acute Care Nurse Practitioner in the MICU and the ICU Recovery Center, Department of Medicine, Vanderbilt University Medical Center. Elizabeth L. Huggins is Acute Care Nurse Practitioner, Department of Medicine, Vanderbilt University Medical Center. Scottie L. Grayson was a patient in the ICU Recovery Center at Vanderbilt University Medical Center. James C. Jackson is Neuropsychologist and Assistant Director of the ICU Recovery Center, Center for Health Services Research, Department of Medicine, Department of Psychiatry, Vanderbilt University Medical Center, and Geriatric Research, Education and Clinical Center (GRECC) Service, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, Tennessee. Carla M. Sevin is Assistant Professor of Medicine and Director of the ICU Recovery Center, Vanderbilt University Medical Center.
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James C. Jackson, PsyD;
James C. Jackson, PsyD
Joanna L. Stollings is Clinical Pharmacy Specialist in the Medical Intensive Care Unit (MICU) and Pharmacist in the ICU Recovery Center, Department of Pharmaceutical Services, Vanderbilt University Medical Center, 1211 Medical Center Drive, BUH-131, Nashville, TN 37232 ([email protected]). Sarah L. Bloom is Acute Care Nurse Practitioner in the MICU and the ICU Recovery Center, Department of Medicine, Vanderbilt University Medical Center. Elizabeth L. Huggins is Acute Care Nurse Practitioner, Department of Medicine, Vanderbilt University Medical Center. Scottie L. Grayson was a patient in the ICU Recovery Center at Vanderbilt University Medical Center. James C. Jackson is Neuropsychologist and Assistant Director of the ICU Recovery Center, Center for Health Services Research, Department of Medicine, Department of Psychiatry, Vanderbilt University Medical Center, and Geriatric Research, Education and Clinical Center (GRECC) Service, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, Tennessee. Carla M. Sevin is Assistant Professor of Medicine and Director of the ICU Recovery Center, Vanderbilt University Medical Center.
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Carla M. Sevin, MD
Carla M. Sevin, MD
Joanna L. Stollings is Clinical Pharmacy Specialist in the Medical Intensive Care Unit (MICU) and Pharmacist in the ICU Recovery Center, Department of Pharmaceutical Services, Vanderbilt University Medical Center, 1211 Medical Center Drive, BUH-131, Nashville, TN 37232 ([email protected]). Sarah L. Bloom is Acute Care Nurse Practitioner in the MICU and the ICU Recovery Center, Department of Medicine, Vanderbilt University Medical Center. Elizabeth L. Huggins is Acute Care Nurse Practitioner, Department of Medicine, Vanderbilt University Medical Center. Scottie L. Grayson was a patient in the ICU Recovery Center at Vanderbilt University Medical Center. James C. Jackson is Neuropsychologist and Assistant Director of the ICU Recovery Center, Center for Health Services Research, Department of Medicine, Department of Psychiatry, Vanderbilt University Medical Center, and Geriatric Research, Education and Clinical Center (GRECC) Service, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, Tennessee. Carla M. Sevin is Assistant Professor of Medicine and Director of the ICU Recovery Center, Vanderbilt University Medical Center.
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AACN Adv Crit Care (2016) 27 (2): 133–140.
Citation
Joanna L. Stollings, Sarah L. Bloom, Elizabeth L. Huggins, Scottie L. Grayson, James C. Jackson, Carla M. Sevin; Medication Management to Ameliorate Post–Intensive Care Syndrome. AACN Adv Crit Care 1 April 2016; 27 (2): 133–140. doi: https://doi.org/10.4037/aacnacc2016931
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