The purpose of the immune system is to protect cells from invasion by microorganisms. The body has three equally important interactive immune defense systems, all of which are profoundly disrupted with major burn injury. The immune response to burn injury is immediate, prolonged, and severe. The end result in individuals surviving burn shock is immunosuppression, with increased susceptibility to potentially fatal systemic burn wound or pulmonary sepsis. Nursing actions to support the humoral and cell-mediated immune system of the burned patient include providing nutritional support to maintain serum protein levels at optimal levels; measures to decrease edema and promote angiogenesis in areas of partial-thickness injury; meticulous treatment of the wound to prevent infection and promote healing; monitoring of antibiotic use; conservative use of invasive techniques, including intubation and vascular access devices; maintenance of fluid and electrolyte balance and body temperature; and energy conservation measures
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Burn Care| May 01 1993
Immune Consequences of Burn Injury
Melva Kravitz, RN, PhD, CCRN
From the Department of Nursing, Veterans Affairs Medical Center, Albuquerque, New Mexico.
Reprint requests to Melva Kravitz, RN, PhD, CCRN, Department of Nursing (118), Veterans Affairs Medical Center, 2100 Ridgecrest Drive SE, Albuquerque, NM 87108.
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AACN Adv Crit Care (1993) 4 (2): 399–413.
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Melva Kravitz; Immune Consequences of Burn Injury. AACN Adv Crit Care 1 May 1993; 4 (2): 399–413. doi: https://doi.org/10.4037/15597768-1993-2017
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