Tailoring medication administration to obtain the optimal chronobiologic function of individuals with respiratory disorders has been studied by numerous researchers. Integration of chronobiologic concepts into therapeutic regimens for patients with chronic airflow obstruction has been, successful in reducing nocturnal symptoms of reduced airflow. Application of chronotherapeutic concepts in administration of commonly used respiratory medications is presented. Pharmacologic and nonpharmacologic chronotherapeutic implications for providing care for critically ill patients with respiratory disorders are discussed

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