Anxiety, fear, and pair are common occurrences for patients with acute respiratory failure. These symptoms’ may influence patients ability to tolerate mechanical ventilation because of the development of asynchronous breathing patterns. The administration of sedatives and neuromusenlar blocking agents may be necessary to facilitate ventilation and enhance oxygenation. Few published protocols exist to guide clinicians in initiating and effectively monitoring patients receiving those agents. In this article, the author focuses on the identification of patients for whom these drugs may be indicated, describes protocols currently available, and offers suggestions for improving patient monitoring to avoid the development of adverse events
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Respiratory Pharmacology| May 01 1995
Sedation and Chemical Relaxation in Critical Pulmonary Illness: Suggestions for Patient Assessment and Drug Monitoring
Jill M. Luer, PharmD
From the Medical Intensive Care Unit, University of Virginia Health Sciences Center, Charlottesville, Virginia.
Reprint requests to Jill M. Luer, PharmD, Clinical Pharmacy Specialist in Adult Medicine, Box 274-11, Medical Intensive Care Unit, University of Virginia Health Sciences Center, Charlottesville, VA 22908.
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AACN Adv Crit Care (1995) 6 (2): 333–343.
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Jill M. Luer; Sedation and Chemical Relaxation in Critical Pulmonary Illness: Suggestions for Patient Assessment and Drug Monitoring. AACN Adv Crit Care 1 May 1995; 6 (2): 333–343. doi:
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