The purpose of this article is threefold: to reveal how a disease that afflictis many critical care patients can be the impetus for forging into a research career; to illustrate a program of research undertaken by a nurse Investigator to answer a critical care nursing question using genetic technology; and to identify exciting opportunities for research training, career development and investigator-initiated research activities for the advanced practice critical care nurse at the National Institute of Nursing Research. The article concludes by identifying future linkages between nursing research and genetics

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