Systemic lupus erythematosus (SLE) is a multisystemic disease of the connective tissue characterized by the presence of numerous antibodies, circulating immune complexes, and deposition of immune complexes in multiple organs. In this case study, the authors describe a patient with a relapse of SLE who had abdominal signs and symptoms mimicking those of an acute abdomen and bizarre-looking findings on angiograms of the superior mesenteric vessels.

Systemic lupus erythematosus (SLE) is a multi-systemic disease of the connective tissue characterized by the presence of numerous antibodies, circulating immune complexes, and deposition of immune complexes in multiple organ systems.1 In addition, a disturbance in the regulation of immunoglobulins occurs, with a defect in suppressor T lymphocytes associated with polyclonal activation of B lymphocytes and the uncontrolled production of autoantibodies and immune complexes.2 

Gastrointestinal vasculitis in SLE is rare and almost always is associated with evidence of active disease in other...

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