Locked-in syndrome is an extremely rare neurological state caused by injury of the ventral pons. The syndrome is characterized by quadriplegia and anarthria with concomitant preservation of cortical function. When a reversible underlying pathological abnormality is identified and managed aggressively, meaningful recovery is possible. Because patients retain consciousness throughout their illness, a dependable method for titrating sedation may improve their quality of life. The case presented suggests that bispectral index monitoring may be a cost-effective and reliable method for managing sedation in patients with locked-in syndrome.
Bispectral Index Monitoring in the Management of Sedation in an Intensive Care Unit Patient With Locked-in Syndrome
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Sadeq A. Quraishi, Sandralee A. Blosser, Robert A. Cherry; Bispectral Index Monitoring in the Management of Sedation in an Intensive Care Unit Patient With Locked-in Syndrome. Am J Crit Care 1 November 2011; 20 (6): 487–490. doi: https://doi.org/10.4037/ajcc2011674
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