Validation of the RightLevelpH Detector for Monitoring Gastric pH

Lambert, Charles R.; Varlotta, David; Posey, Marjorie; Heberlein, Jadie L.; Shirley, Janice M.

doi:10.4037/ajcc2015211

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Critical Care Evaluation| May 01 2015

Validation of the RightLevelpH Detector for Monitoring Gastric pH

Charles R. Lambert, MD, PhD, MBA;

Charles R. Lambert, MD, PhD, MBA

Charles R. Lambert is the medical director of Florida Hospital Tampa Pepin Heart Institute and the Dr Kiran C. Patel Research Institute, Tampa, Florida, and professor of medicine, Division of Cardiovascular Medicine, University of Florida, Gainesville, Florida. David Varlotta is a staff anesthesiologist, Marjorie Posey and Jadie L. Heberlein are clinical research nurses, and Janice M. Shirley is administrative director of research, Florida Hospital Tampa Pepin Heart Institute and the Dr Kiran C. Patel Research Institute.

Corresponding author: Dr Charles Lambert, Florida Hospital Tampa Pepin Heart Institute, 3100 E Fletcher Ave, Tampa, Florida 33613 (e-mail: [email protected]).

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David Varlotta, DO;

David Varlotta, DO

Charles R. Lambert is the medical director of Florida Hospital Tampa Pepin Heart Institute and the Dr Kiran C. Patel Research Institute, Tampa, Florida, and professor of medicine, Division of Cardiovascular Medicine, University of Florida, Gainesville, Florida. David Varlotta is a staff anesthesiologist, Marjorie Posey and Jadie L. Heberlein are clinical research nurses, and Janice M. Shirley is administrative director of research, Florida Hospital Tampa Pepin Heart Institute and the Dr Kiran C. Patel Research Institute.

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Marjorie Posey, BSN;

Marjorie Posey, BSN

Charles R. Lambert is the medical director of Florida Hospital Tampa Pepin Heart Institute and the Dr Kiran C. Patel Research Institute, Tampa, Florida, and professor of medicine, Division of Cardiovascular Medicine, University of Florida, Gainesville, Florida. David Varlotta is a staff anesthesiologist, Marjorie Posey and Jadie L. Heberlein are clinical research nurses, and Janice M. Shirley is administrative director of research, Florida Hospital Tampa Pepin Heart Institute and the Dr Kiran C. Patel Research Institute.

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Jadie L. Heberlein, BSN, MPH;

Jadie L. Heberlein, BSN, MPH

Charles R. Lambert is the medical director of Florida Hospital Tampa Pepin Heart Institute and the Dr Kiran C. Patel Research Institute, Tampa, Florida, and professor of medicine, Division of Cardiovascular Medicine, University of Florida, Gainesville, Florida. David Varlotta is a staff anesthesiologist, Marjorie Posey and Jadie L. Heberlein are clinical research nurses, and Janice M. Shirley is administrative director of research, Florida Hospital Tampa Pepin Heart Institute and the Dr Kiran C. Patel Research Institute.

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Janice M. Shirley, MPH, MBA

Charles R. Lambert is the medical director of Florida Hospital Tampa Pepin Heart Institute and the Dr Kiran C. Patel Research Institute, Tampa, Florida, and professor of medicine, Division of Cardiovascular Medicine, University of Florida, Gainesville, Florida. David Varlotta is a staff anesthesiologist, Marjorie Posey and Jadie L. Heberlein are clinical research nurses, and Janice M. Shirley is administrative director of research, Florida Hospital Tampa Pepin Heart Institute and the Dr Kiran C. Patel Research Institute.

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Am J Crit Care (2015) 24 (3): 211–215.

https://doi.org/10.4037/ajcc2015211

Background

The RightLevelpH indicator is a new device designed to measure the pH of gastric aspirate obtained via a nasogastric tube while minimizing exposure of the operator.

Objective

To validate the RightLevelpH indicator in vivo and in vitro.

Methods

With general anesthesia, 20 patients had placement of a nasogastric tube and a gastric pH electrode catheter after endotracheal intubation. Direct intragastric pH was recorded simultaneously with gastric aspirate pH by using the RightLevelpH indicator and by using an external pH electrode. Measurements were made every 30 minutes until removal of the nasogastric tube as indicated clinically. In vitro validation of the RightLevelpH indicator was performed by using standard buffer solutions.

Results

The pH of clear buffer solutions was linearly related to pH determined by the RightLevelpH indicator (R² = 0.99; P < .001). The pH of gastric aspirate determined with an external pH electrode was linearly related to the gastric aspirate pH determined by using the RightLevelpH indicator (R² = 0.92; P < .001). Intragastric pH determined with the catheter electrode was also linearly related but more loosely correlated with gastric aspirate pH determined by using an external pH electrode (R² = 0.52; P < .001) and by the RightLevelpH indicator (R² = 0.55; P < .001).

Conclusions

The RightLevelpH indicator provides accurate measurements of the pH of gastric aspirate in patients.

2015

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