Pediatric traumatic brain injury (TBI) protocols vary widely among institutions, despite the existence of published guidelines. This study seeks to identify significant differences in management of pediatric TBI across several institutions. Severe pediatric TBI protocols were collected from major US pediatric hospitals through direct communication with trauma staff. Of 24 institutions identified and contacted, 10 did not respond and 5 did not have a pediatric TBI protocol. Pediatric TBI protocols were successfully collected from 9 institutions. These 9 protocols were separated into treatment tiers analogous to those in the 2019 Society of Critical Care Medicine and World Federation of Pediatric Intensive and Critical Care Societies guidelines, and the intervention variables were identified and compared across the 9 institutions. First-line therapies were similar between institutions, including seizure prophylaxis, maintenance of normoglycemia and normothermia, and avoidance of hypoxia, hyponatremia, and hypotension. However, significant variation across institutions was found regarding timing of cerebrospinal fluid drainage, hyperventilation, and neuromuscular blockade. When included in institutional protocols, most therapies are in line with the 2019 guidelines, except for diversion of cerebrospinal fluid, hyperventilation, maintenance of cerebral perfusion pressure, and use of neuromuscular blocking agents. Although these variations may represent differences in style or preference, the optimal timing of these specific treatment variations should be studied to determine the impact of each protocol on clinical outcomes.
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1 September 2021
Brief Report|
September 01 2021
Adherence to Guidelines for Managing Severe Traumatic Brain Injury in Children
Hengameh B. Pajer, MS;
Hengameh B. Pajer, MS
Hengameh B. Pajer is a medical student, Campbell University School of Osteopathic Medicine, Buis Creek, North Carolina.
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Anthony M. Asher, BA;
Anthony M. Asher, BA
Anthony M. Asher is a medical student, University of North Carolina School of Medicine, Chapel Hill.
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Dennis Leung, MD;
Dennis Leung, MD
Dennis Leung is a fellow, Department of Pediatric Critical Care, University of North Carolina, Chapel Hill.
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Randaline R. Barnett, MD;
Randaline R. Barnett, MD
Randaline R. Barnett is a resident, Department of Neurosurgery, University of North Carolina, Chapel Hill.
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Benny L. Joyner, Jr, MD, MPH;
Benny L. Joyner, Jr, MD, MPH
Benny L. Joyner Jr is a professor, Department of Pediatric Critical Care, University of North Carolina, Chapel Hill.
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Carolyn S. Quinsey, MD
Carolyn S. Quinsey is an assistant professor and associate program director, Department of Neurosurgery, University of North Carolina, Chapel Hill.
Corresponding author: Carolyn Quinsey, MD, 101 Manning Dr, Chapel Hill, NC 27514 (email: [email protected]).
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Am J Crit Care (2021) 30 (5): 402–406.
Citation
Hengameh B. Pajer, Anthony M. Asher, Dennis Leung, Randaline R. Barnett, Benny L. Joyner, Carolyn S. Quinsey; Adherence to Guidelines for Managing Severe Traumatic Brain Injury in Children. Am J Crit Care 1 September 2021; 30 (5): 402–406. doi: https://doi.org/10.4037/ajcc2021111
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