Clinical deterioration remains a significant challenge for health care systems, with studies consistently demonstrating that warning signs precede adverse events that result in increased risk of morbidity and mortality. Rapid response systems (RRSs) have become a standard approach to address this issue by deploying specialized teams to identify and intervene when patients show signs of decline. Despite widespread adoption, questions persist about the effectiveness of RRSs in reducing mortality and their economic impact. The heterogeneity in RRS implementation has confounded results, leaving uncertainty about RRSs’ overall effectiveness and impact on outcomes. Systems vary in their ability to manage adverse events, with studies suggesting that ability to rescue clinically deteriorating patients is a measure of organizational competence. This review is intended to evaluate clinical evidence for RRSs and describe emerging innovations in the field.

The search strategy included PubMed, CINAHL, and Google Scholar for peer-reviewed publications...

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