Pressure control ventilation and airway pressure release ventilation, a form of pressure control ventilation, have similar breath delivery patterns (square wave) that allow for early and sustained achievement of the set inspiratory pressure until exhalation. This breath pattern combined with inverse ratio (short expiratory time) can recruit the significant alveolar collapse associated with ARDS.

Both PAV and NAVA are modes that provide ventilator support in proportion to the patient’s effort. These modes are designed to be more responsive to the patient in triggering the supported breath. Most of the evidence is in improved patient-ventilator synchrony over pressure support ventilation. Both PAV and NAVA are limited to only a few manufactured machines.

Pressure-regulated volume control is a dual-control or volume-targeted pressure mode. In switching from standard volume control ventilation to a dual-control mode, the target tidal volume can often be achieved at a lower inspiratory pressure. The machine optimizes the delivery...

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